| Rnk | LW* | Team | Record | Comments |
| 1. | 1. | Denver Broncos | 4-0 | Manning is at the top of his game. |
| 2. | 2. | Seattle Seahawks | 4-0 | Undefeated after 4 games for the first time in franchise history. |
| 3. | 3. | New Orleans Saints | 4-0 | Scapegoating of Ryan last season in Dallas looking more and more ridiculous. |
| 4. | 4. | New England Patriots | 4-0 | Loss of Wilfork is a blow. |
| 5. | 9. | Kansas City Chiefs | 4-0 | Feasting on the NFC East. |
| 6. | 11. | Indianapolis Colts | 3-1 | How lucky was this franchise to be in a position to draft Manning and then Luck in succession. |
| 7. | 16. | Detriot Lions | 3-1 | Stafford has won 8 of his 9 meetings with the Bears. |
| 8. | 5. | Chicago Bears | 3-1 | Cutler wilted under the pressure of Suh and Fairley. |
| 9. | 12. | San Francisco 49ers | 2-2 | Need to get Kaepernick untracked. |
| 10. | 10. | Miami Dolphins | 3-1 | How will they handle short work week after first loss? |
| 11. | 17. | Tennessee Titans | 3-1 | Can Fitzpatrick hold down the fort while Locker recovers from hip injury? |
| 12. | 6. | Cincinnati Bengals | 2-2 | Shockingly lost the battle of Ohio in the muddled AFC North. |
| 13. | 7. | Baltimore Ravens | 2-2 | Done in by Flacco's 5 interceptions. |
| 14. | 14. | Green Bay Packers | 1-2 | Come off the bye with a must win in Lambeau against the surging Lions. |
| 15. | 8. | Houston Texans | 2-2 | Schaub got booed off the field after ill-advised pick 6 led to overtime loss. |
| 16. | 15. | Atlanta Falcons | 1-3 | Need to get back on track in the next 3 games against the Jets, Bucs and Cards. |
| 17. | 21. | San Diego Chargers | 2-2 | Whisenhunt has helped Rivers get his mojo back. |
| 18. | 13. | Dallas Cowboys | 2-2 | Pass defense remains their Achilles heel. |
| 19. | 19. | Arizona Cardinals | 2-2 | Found a way to win on the East coast despite running only 59 plays with 25:55 time of possession. |
| 20. | 23. | Buffalo Bills | 2-2 | Defense made Flacco look bad. |
| 21. | 26. | Washington Redskins | 1-3 | Saved their season in Oakland. |
| 22. | 28. | Cleveland Browns | 2-2 | Horton deserves credit for defensive revival. |
| 23. | 18. | St. Louis Rams | 1-3 | Hamstrung by Bradford's failure to take the next step. |
| 24. | 24. | Carolina Panthers | 1-2 | Can they continue to roll on offense after the bye? |
| 25. | 20. | New York Jets | 2-2 | Let Smith take his lumps in Tennessee. Will he learn from his mistakes? |
| 26. | 29. | Minnesota Vikings | 1-3 | Benefited from Ponder's absence. |
| 27. | 22. | Philadelphia Eagles | 1-3 | Kelly did not know what he was getting himself into. |
| 28. | 25. | New York Giants | 0-4 | Have been outscored by 109 points. At least their division stinks. |
| 29. | 27. | Pittsburgh Steelers | 0-4 | Last time they were 0-4 was '68. Like the Giants at least their division stinks. |
| 30. | 30. | Oakland Raiders | 1-3 | Now we know why Flynn keeps losing his job in preseason. |
| 31. | 31. | Tampa Bay Buccaneers | 0-4 | Decision to have rookie Glennon throw the ball while trying to ice the game backfired. |
| 32. | 32. | Jacksonville Jaguars | 0-4 | Could they beat Alabama? |
*Last week's ranking